Three Lines of Defense in Immunity

i. First Line of Defense

  • Skin
  • Mucous Membranes
  • Secretions

ii. Second Line of Defense

  • Phagocytosis
  • Inflammation
  • Fever
  • Complement System
  • Natural Killer (NK) Cells

iii. Third Line of Defense

  • B Lymphocytes
  • T Lymphocytes
  • Immunological Memory